HIV & Long COVID

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    Overview

    People living with HIV are 2-4x more likely to get Long COVID.

    As we saw with the emergence of HIV/AIDS, pandemics expose the critical need for large-scale change in healthcare, public health, and unjust structures that bring inequitable risks of illness, suffering, and mortality.

    Even as the COVID and HIV pandemics continue to claim lives, we are pressured to return to a “business as normal” that has never centered the needs of disabled people and people with complex chronic conditions. Pandemics disproportionately impact already marginalized communities, including Black, Brown and indigenous people, immigrants, queer and trans people, older people, poor and low-income people, those who are imprisoned and those without access to stable housing.

    We need to keep talking about the intersections between HIV and Long COVID – and other infection-associated chronic illnesses like ME/CFS, MCAS, and POTS – and we need to keep organizing, advocating, and fighting for health justice.

    Why might people with HIV be at higher risk for Long COVID?

    Possible factors might include:

    • More severe COVID-19 (especially if viremic or low CD+4 T cell count)
    • Chronic comorbid conditions (diabetes, heart disease, neurocognitive disorder, mental health conditions, substance use)
    • Socioeconomic factors (income, food security, healthcare access)
    • HIV virus-specific activity (viral control, medication regimen)
    • HIV-associated immune dysfunction & different immune responses to COVID-19 infection
    • Baseline inflammation due to chronic HIV infection

    Living with HIV and concerned you might have Long COVID?

    Tips for talking to your medical providers:

    • “Since I had COVID, I am experiencing [symptom], which I did not have before I had COVID.” “
    • “My [symptom] is much worse than before I had COVID.”
    • “Do you think I could have Long COVID?”
    • “Are there any tests that you think I should do to make sure there is nothing else going on?


    Source: presentation by Dr. Michael Peluso from our 7/17/23 webinar


    Resources

    Webinars

    Additional Reading

    Social posts

    1. Long COVID Definition | National Academies of Sciences, Engineering and Medicine (2024)
    2. Long COVID and Significant Activity Limitation Among Adults, by Age — United States, June 1–13, 2022, to June 7–19, 2023 | CDC – MMW
    3. SARS-CoV-2 Reinfections and Long COVID in the Post-Omicron Phase of the Pandemic | Institutional Journal of Molecular Sciences
    4. More evidence that long COVID is more common in people with HIV | aidsmap
    5. COVID-19 Treatment Guidelines: Special Considerations in People With HIV | NIH
    6. Long COVID: rheumatologic/musculoskeletal symptoms in hospitalized COVID-19 survivors at 3 and 6 months | National Library of Medicine – PMC
    7. HIV and inflammatory markers are associated with persistent COVID‐19 symptoms | National Library of Medicine – PMC
    8. Vaccines for Moderately to Severely Immunocompromised People | CDC
    9. Vaccines for Moderately to Severely Immunocompromised People | CDC
    10. Guidance for COVID-19 and People With HIV | HIV.gov
    11. https://www.cdc.gov/hiv/basics/covid-19.html
    12. Association of Treatment With Nirmatrelvir and the Risk of Post–COVID-19 Condition | Clinical Pharmacy and Pharmacology | JAMA Internal Medicine
    13. Metformin-COVID Handout | Parsemus.org
    14. Fastlab- Rapid and PCR Test Delivery | FastLab
    15. COVID-19: Express Testing | NYC Health
    16. Managing COVID-19 in People With HIV (Paxlovid-HIV) | NIH
    17. COVID-19 Treatment Guidelines: Special Considerations in People With HIV | NIH
    18. Characteristics and impact of Long Covid: Findings from an online survey | National Library of Medicine – PMC


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